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The Multiplate MEA Analyzer (Roche Diagnostics International Ltd) has 5 channels for simultaneous measurement of several samples or agonists. The instrument detects change in electrical impedance when platelets aggregate on metal electrodes in the test cuvette. Each cuvette contains two pairs of sensor electrodes, each of which measures the ...
In 2009, Roche launched the GS Junior, a bench top version of the 454 sequencer with read length up to 400bp, and simplified library preparation and data processing. One of the advantages of 454 systems is their running speed. Manpower can be reduced with automation of library preparation and semi-automation of emulsion PCR.
The Roche Institute of Molecular Biology was created on July 14, 1967 when John Burns, then the vice president of research at Hoffman-La Roche, persuaded biochemist Sidney Udenfriend to leave the National Institutes of Health and help him create a basic science institute at the Hoffman-La Roche Nutley, New Jersey, facility. It lasted for 28 ...
Both + Ends-free: P. Aboyoun: 2008 BioPerl dpAlign Dynamic programming: Both: Both + Ends-free: Y. M. Chan: 2003 BLASTZ, LASTZ Seeded pattern-matching: Nucleotide: Local: Schwartz et al. [18] [19] 2004,2009 CUDAlign DNA sequence alignment of unrestricted size in single or multiple GPUs Nucleotide: Local, SemiGlobal, Global: E. Sandes [20] [21 ...
Roche acquired Syntex in 1994, and Chugai Pharmaceuticals in 2002. Oseltamivir an antiviral drug used to combat influenza. Roche is the only drug company authorized to manufacture the drug, which was discovered by Gilead Sciences. Roche purchased the rights to the drug in 1996, and in 2005, settled a royalty dispute, agreeing to pay Gilead ...
[42] [43] [44] KOD polymerase and some modified thermostable DNA polymerases (iProof/Phusion, Pfu Ultra, Velocity or Z-Taq) are used as a PCR variant with shorter amplification cycles (fast PCR, high-speed PCR) due to their high synthesis rate. Processivity describes the average number of base pairs before a polymerase falls off the DNA template.
Pyrosequencing is a method of DNA sequencing (determining the order of nucleotides in DNA) based on the "sequencing by synthesis" principle, in which the sequencing is performed by detecting the nucleotide incorporated by a DNA polymerase.
The cost of benchmarking can substantially be reduced through utilizing the many internet resources that have sprung up over the last few years. These aim to capture benchmarks and best practices from organizations, business sectors and countries to make the benchmarking process much quicker and cheaper. [9]