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Hinton developed a flocculation test for syphilis in 1927, and co-developed another syphilis test using spinal fluid with a colleague that would come to be known as the Davies-Hinton test. These tests were considered a boon for medicine, as the treatment for syphilis at the time was long, painful, and hazardous.
The Wassermann test or Wassermann reaction (WR) [1] is an antibody test for syphilis, named after the bacteriologist August Paul von Wassermann, based on complement fixation. It was the first blood test for syphilis and the first in the nontreponemal test (NTT) category. Newer NTTs, such as the RPR and VDRL tests, have mostly replaced it.
Some researchers argued that syphilis was carried from the New World to Europe after Columbus' voyages, while others argue the disease has a much longer history in Europe. Many of the crew members who served on this voyage later joined the army of King Charles VIII in his invasion of Italy in 1495, which some argue may have resulted in the ...
The new test received FDA authorization after the company submitted data from clinical trials showing that the First To Know Syphilis Test identified a positive specimen 93.4% of the time.
Syphilis has been known as "the great imitator", because it may cause symptoms similar to many other diseases. [2] [3] Syphilis is most commonly spread through sexual activity. [2] It may also be transmitted from mother to baby during pregnancy or at birth, resulting in congenital syphilis.
A subject of the Tuskegee syphilis experiment has his blood drawn, c. 1953.. Numerous experiments which were performed on human test subjects in the United States in the past are now considered to have been unethical, because they were performed without the knowledge or informed consent of the test subjects. [1]
Syphilis is treatable with antibiotics. However, if left untreated, it can progress through several stages and lead to a wide range of health issues. Houston sees 128% increase in syphilis cases ...
Often a plastic test plate containing many small "wells" is used as the test dish so that many patients may be tested at the same time but their results can be kept separate from each other. Please note the image (Fig 1) of the wells on the test plate and the positive and negative test results look different. [1] For primary syphilis, TPPA has ...
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