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While Beau's lines are actual ridges and indentations in the nail plate, Muehrcke lines are areas of hypopigmentation without palpable ridges; they affect the underlying nail bed, and not the nail itself. Beau's lines should also be distinguished from Mees' lines of the fingernails, which are areas of discoloration in the nail plate.
First, a crash course on what fingernail ridges even are: Vertical nail ridges (lines that run from your cuticle to the tip of your fingernail) are super-common, and are a normal sign of aging.
What are ridges in fingernails? “Ridges in the fingernails are vertical or horizontal depressions on the nail plate,” says Angela Kim, D.O., a board-certified dermatologist practicing in Yuba ...
Iron-deficiency anemia can lead to a pale color along with a thin, brittle, ridged texture. Iron deficiency in general may cause the nails to become flat or concave, rather than convex. As oxygen is needed for healthy nails, an iron deficiency or anemia can lead to vertical ridges or concavity in the nails. [28]
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Muehrcke's lines were described by American physician Robert C. Muehrcke (1921–2003) in 1956. In a study published in BMJ, he examined patients with known chronic hypoalbuminemia and healthy volunteers, finding that the appearance of multiple transverse white lines was a highly specific marker for low serum albumin (no subject with the sign had SA over 2.2 g/dL), was associated with severity ...
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"The longitudinal striations can occur as a normal part of the aging process", [2] and not until the nails start to thin and get a sandpaper look is the condition called trachonychia. The nails are opalescent and frequently are brittle and split at the free margin. There has been evidence of the condition as a cutaneous manifestation of lichen ...