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Subcutaneous fat necrosis of the newborn is a rare form of lobular panniculitis occurring in newborns that is usually self-remitting and non-recurring. Proposed causes include perinatal stress, local trauma, hypoxia and hypothermia , though the exact cause is unknown.
Subcutaneous fat necrosis of the newborn This page was last edited on 30 December 2019, at 05:41 (UTC). Text is available under the Creative Commons ...
Fat necrosis may result from various injuries to adipose tissue, including: physical trauma, enzymatic digestion of adipocytes by lipases, [3] radiation therapy, [4] hypoxia, or inflammation of subcutaneous fat (panniculitis). The gross appearance of fat necrosis is as an irregular, chalky white area within otherwise normal adipose tissue. [1]
Necrosis of subcutaneous fat without a significant inflammatory infiltrate and without obvious granulomatous changes, the formation of needle-shaped clefts in adipocytes, sometimes in a radial arrangement, and fibrous thickening of the tissue surrounding fat lobules are histopathologic findings that support a diagnosis of sclerema neonatorum.
Pancreatic panniculitis (also known as enzymatic panniculitis, Pancreatic fat necrosis, [10] and subcutaneous fat necrosis) is a panniculitis most commonly associated with pancreatic carcinoma, and more rarely with anatomic pancreatic abnormalities, pseudocysts, or drug-induced pancreatitis. [2]: 493
Subcutaneous fat. A majority of fat (90%) is subcutaneous fat, which is the layer of fat closest to the skin. Since it’s stored right under your skin, ...
Erythema nodosum (EN) is an inflammatory condition characterized by inflammation of subcutaneous fat tissue, resulting in painful red/blue lumps or nodules that are usually seen symmetrically on both shins, on the thighs, arms, and elsewhere. [1] It can be caused by a variety of conditions but 20 to 50% of cases are idiopathic.
Septal panniculitis is a condition of the subcutaneous fat affecting the layer of adipose tissue that lies between the dermis and underlying fascia, of which there are two forms: acute erythema nodosum and chronic erythema nodosum. [1]: 487–9