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  2. Management of heart failure - Wikipedia

    en.wikipedia.org/wiki/Management_of_heart_failure

    Sleep apnea is an under-recognized risk factor for heart failure. Uncontrolled sleep apnea may increase the risk of heart failure by up to 140%. [4] Weight reduction – through physical activity and dietary modification, as obesity is a risk factor for heart failure and left ventricular hypertrophy. Effective weight management has been shown ...

  3. Vericiguat - Wikipedia

    en.wikipedia.org/wiki/Vericiguat

    Vericiguat, sold under the brand name Verquvo, is a medication used to reduce the risk of cardiovascular death and hospitalization in certain patients with heart failure after a recent acute decompensation event. [3] [4] [8] It is taken by mouth. [3] [4] [8] Vericiguat is a soluble guanylate cyclase (sGC) stimulator. [3]

  4. Cardiotonic agent - Wikipedia

    en.wikipedia.org/wiki/Cardiotonic_agent

    Cardiotonic agents are typically employed as short-term and non-routine therapies for heart failure patients. [71] They are specifically reserved for those with contractile dysfunction in the left ventricles (lower chambers of the heart), low cardiac output, and low blood pressure, placing them at risk of inadequate organ perfusion. [72]

  5. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    Heart failure - Giving 2.5 times of previous oral dose twice daily for those with acute decompensated heart failure is a reasonable strategy. However, daily assessment of clinical response is needed to adjust the subsequent doses. [6] Edema - Volume overload associated with liver cirrhosis, heart failure, or nephrotic syndrome [11]

  6. Sacubitril/valsartan - Wikipedia

    en.wikipedia.org/wiki/Sacubitril/valsartan

    [10] [11] [18] To investigate its use for heart failure in those with a preserved LVEF (HFpEF), Novartis funded the PARAGON-HF trial which was designed to investigate the use of sacubitril/valsartan in the treatment of HFpEF patients with a LVEF of 45% or more. Concluding in 2019, it failed to show significance for reducing hospitalisation ...

  7. Commonly prescribed drugs - Wikipedia

    en.wikipedia.org/wiki/Commonly_prescribed_drugs

    Commonly prescribed drugs are prescribed according to guidelines around the world. For instance, for ischemic heart disease, the American College of Cardiology/American Heart Association (ACC/AHA) guideline is used in the United States and the European Society of Cardiology (ESC) guideline is used in Europe.

  8. Isosorbide dinitrate - Wikipedia

    en.wikipedia.org/wiki/Isosorbide_dinitrate

    Isosorbide dinitrate is a medication used for heart failure, esophageal spasms, and to treat and prevent chest pain from not enough blood flow to the heart. [1] It has been found to be particularly useful in heart failure due to systolic dysfunction together with hydralazine. [2] [1] It is taken by mouth or under the tongue. [1]

  9. PDE3 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE3_inhibitor

    PDE3 inhibitors are indicated as inotropics for the therapy of acute heart failure if catecholamines are ineffective. [2] Well controlled studies have shown that these drugs generally increase mortality , [ 3 ] when used for the therapy of acute heart failure, so they have to be applied under close observation.

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