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A Cochrane review, though, found that metformin was only slightly effective for decreasing androgen levels in women with PCOS. [124] Metformin also has significant effects on the gut microbiome, such as its effect on increasing agmatine production by gut bacteria, but the relative importance of this mechanism compared to other mechanisms is ...
One theory is that metformin has anti-tumor side effects because it lowers insulin levels and keeps tumor cells from multiplying. Still, more research is needed. ... Indeed, many women with PCOS ...
As noted, timing your metformin dosage is crucial for mitigating the risk — and overall severity — of side effects. But what are those side effects exactly? The most common side effects of ...
Metformin is one of the most common first-line medications for type 2 diabetes. Side effects of diabetes medications can include weight loss. ... Aside from knowing the signs of diabetes in women ...
An example of this is the repurposing of the antimineralocorticoid and diuretic spironolactone, which was found to produce feminization and gynecomastia as side effects, for use as an antiandrogen in the treatment of androgen-dependent conditions like acne and hirsutism in women. [1] Metformin also causes off-target activity. [citation needed]
For example, a 2017 study looked at 73 women with obesity who either took 1000mg of metformin or 360mg of orlistat — another weight loss medication — for three months. Although the group ...
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