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The muscle weakness that worsens with activity (abnormal muscle fatigue) in myasthenia gravis [67] is a symptom shared by other neuromuscular diseases. Most of the metabolic myopathies , such as McArdle disease (GSD-V), have abnormal muscle fatigue rather than fixed muscle weakness.
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
Symptoms that are commonly associated with autoimmune diseases include: [11] fatigue. This is the most common complaint of people with autoimmune disease. [12] A 2015 US survey found that 98% of people with autoimmune diseases experienced fatigue, 89% said it was a "major issue", 68% said "fatigue is anything but normal.
There are more than 80 autoimmune conditions (lupus, rheumatoid arthritis, celiac disease, and multiple sclerosis are a few), but they have one thing in common: inflammation.
In diseases such as myasthenia gravis, the end plate potential (EPP) fails to effectively activate the muscle fiber due to an autoimmune reaction against acetylcholine receptors, resulting in muscle weakness and fatigue. [2] Myasthenia gravis is caused most commonly by auto-antibodies against the acetylcholine receptor.
2. Autoimmune Disease. Autoimmune diseases like lupus, rheumatoid arthritis, and type 1 diabetes occur when your immune system mistakenly attacks the healthy cells of your organs and tissues ...
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