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Neurobiology of Aging is a peer-reviewed monthly scientific journal published by Elsevier. The editor-in-chief is Peter R. Rapp. Neurobiology of Aging publishes research in which the primary emphasis addresses the mechanisms of nervous system-changes during aging and in age-related diseases .
1977 To explain aging, Thomas Kirkwood proposed the disposable soma theory. According to the theory, the organism has only a limited amount of resources that it has to allocate between different purposes (such as growth, reproduction, repair of damage). Aging occurs due to the limitation of resources that the body can afford to spend on repair. [4]
Aging is associated with many changes in the central nervous system, such as mild atrophy of the cortex, which is considered non-pathological. Aging is also associated with many neurological and neurodegenerative diseases, such as amyotrophic lateral sclerosis , dementia , mild cognitive impairment , Parkinson's disease , and Creutzfeldt ...
The researchers found that people whose essays about aging involved a lot of “I-talk” — the use of “I” and related words like “my” — were more likely to have poor well-being.
The ability of an individual to demonstrate attenuated cognitive signs of aging despite an aging brain is called cognitive reserve. [ 22 ] [ 69 ] This hypothesis suggests that two patients might have the same brain pathology, with one person experiencing noticeable clinical symptoms, while the other continues to function relatively normally.
The Journal of Nutrition, Health and Aging; ... Neurobiology of Aging; P. Physical & Occupational Therapy in Geriatrics; Psychology and Aging; R. Rejuvenation Research;
It has been proposed that DNA damage accumulation provides the underlying causative link between aging and neurodegenerative disease. [ 55 ] [ 56 ] About 20–40% of healthy people between 60 and 78 years old experience discernable decrements in cognitive performance in several domains including working, spatial, and episodic memory, and ...
Studies comparing the effects of aging on episodic memory, semantic memory, short-term memory and priming find that episodic memory is especially impaired in normal aging; some types of short-term memory are also impaired. [9] The deficits may be related to impairments seen in the ability to refresh recently processed information. [10]