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Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [ 1 ] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.
Intravenous (IV) iron infusion is a therapy in which a combination of iron and saline solution is delivered directly into the bloodstream through a vein, in patients suffering iron deficiency, iron-deficiency anaemia and chronic kidney disease. [ 1 ][ 2 ][ 3 ] IV iron infusions are recommended when oral iron supplementation fails to adequately ...
Iron poisoning typically occurs from ingestion of excess iron that results in acute toxicity. Mild symptoms which occur within hours include vomiting, diarrhea, abdominal pain, and drowsiness. [1] In more severe cases, symptoms can include tachypnea, low blood pressure, seizures, or coma. [2] If left untreated, acute iron poisoning can lead to ...
Nephrotic syndrome is a collection of symptoms due to kidney damage. This includes protein in the urine, low blood albumin levels, high blood lipids, and significant swelling. Other symptoms may include weight gain, feeling tired, and foamy urine. Complications may include blood clots, infections, and high blood pressure.
“Kidney disease is a silent killer, so many do not have any signs of kidney disease until they are in the late stages of the disease,” she says. For this reason, nine in 10 people with chronic ...
New research has reassuring findings. There's never been a safer time to give a kidney. The risk of death for people who donated a kidney has dropped by more than half in the last decade ...
Iron sucrose is a dark brown liquid solution. It is administered intravenously and is only used when a patient with iron deficiency cannot be treated using oral iron options. [5] It is a generally effective drug, with more than 80% of patients responding to treatment. Iron sucrose has ~20 mg of iron per mL of solution.
Anemia can be temporary or long term and can range from mild to severe. [6] Anemia can be caused by blood loss, decreased red blood cell production, and increased red blood cell breakdown.[1] Causes of blood loss include bleeding due to inflammation of the stomach or intestines, bleeding from surgery, serious injury, or blood donation.[1 ...