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Nirmatrelvir belongs to a family of 3C-like protease inhibitors developed in the late 2010s against feline coronavirus, while ritonavir is an antiretroviral drug developed in the 1980s and used since the 1990s to inhibit the enzyme that metabolizes other protease inhibitors.
Cumulative incidence curves for symptomatic COVID‑19 infections after the first dose of the Pfizer–BioNTech vaccine (tozinameran) or placebo in a double-blind clinical trial (red: placebo; blue: tozinameran) [196] At 14 days after dose 1, the cumulative incidence begins to diverge between the vaccinated group and the placebo group.
The Janssen COVID‑19 vaccine, (Ad26.COV2.S) sold under the brand name Jcovden, [ 1 ] is a COVID‑19 vaccine that was developed by Janssen Vaccines in Leiden, Netherlands, [ 24 ] and its Belgian parent company Janssen Pharmaceuticals, [ 25 ] a subsidiary of American company Johnson & Johnson. [ 26 ][ 27 ][ 28 ] It is a viral vector vaccine ...
In the United States, remdesivir is indicated for the treatment of COVID‑19 in people 28 days of age and older and weighing at least 3 kilograms (6.6 lb) who are hospitalized; or not hospitalized and have mild-to-moderate COVID‑19, and are at high risk for progression to severe COVID‑19, including hospitalization or death. [ 12 ][ 26 ] In ...
The Oxford–AstraZeneca COVID‑19 vaccine is used to provide protection against infection by the SARS-CoV-2 virus in order to prevent COVID-19 in adults aged 18 years and older. [ 1 ] The medicine is administered by two 0.5 ml (0.017 US fl oz) doses given by intramuscular injection into the deltoid muscle (upper arm).
In July 2020, the UK government signed up for 60 million doses of a COVID-19 vaccine developed by GSK and Sanofi. It uses a recombinant protein -based technology from Sanofi and GSK's pandemic technology. The companies claimed to be able to produce one billion doses, subject to successful trials and regulatory approval, during the first half of ...
[168] [169] The vaccine is known as "COVID-19 Vaccine Moderna Intramuscular Injection". [170] [3] In May 2021, COVID‑19 Vaccine Moderna Intramuscular Injection (formerly TAK-919) was authorized for emergency use in Japan. [3] In June 2021, the Moderna COVID‑19 vaccine was authorized for use in India by the Drugs Controller General of India ...
The Oxford–AstraZeneca COVID-19 vaccine, sold under the brand names Vaxzevria[6]and Covishield,[7]is a viral vector vaccine[8]produced by the British University of Oxford, British-Swedish company AstraZeneca, and the Coalition for Epidemic Preparedness Innovations. [8][9][10]Finland, Denmark, and Norway suspended the use of the Oxford ...
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