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Polysorbate 80 is a surfactant and solubilizer used in a variety of oral and topical pharmaceutical products. Polysorbate 80 is also an excipient that is used to stabilize aqueous formulations of medications for parenteral administration, and used as an emulsifier in the making of the antiarrhythmic amiodarone . [ 9 ]
Polysorbate 80 (polyoxyethylene (20) sorbitan monooleate) The number following the 'polysorbate' part is related to the type of major fatty acid associated with the molecule. Monolaurate is indicated by 20, monopalmitate is indicated by 40, monostearate by 60, and monooleate by 80.
Sorbitan monopalmitate (SMP) is a food additive, [2] permitted by the EU. It is entry E495 in the E number list of permitted food additives. [ 3 ] It is also known under the trade name Span 40.
‘I’m a Reproductive Oncologist, and This is the One Vitamin I’m Suggesting My Patients to Get More Of’
The U.S. Food and Drug Administration (FDA) on Thursday approved a new type of prescription pain medication for adults to treat moderate to severe acute pain. The drug, called Journavx ...
Coating these polymeric nanoparticle devices with different surfactants can also aid BBB crossing and uptake in the brain. Surfactants such as polysorbate 80, 20, 40, 60, and poloxamer 188, demonstrated positive drug delivery through the blood–brain barrier, whereas other surfactants did not yield the same results. [2]
Teeth whitening products can sometimes be a hit or miss, but there's a lot to love about the MySmile Teeth Whitening Pen, which pledges to get rid of stains from smoking, coffee, and wine.
Polysorbate 20 is used by philatelists to remove stamps from envelopes and to remove residues from stamps, without harming the stamp itself. Polysorbate 20 is also used as wetting agent in rubber balers in the elastomer industry. Polysorbate 20 has been used as a shape directing agent to synthesize spheroidal magnetite nanoassemblies. [5]