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  2. Scanning electron microscope - Wikipedia

    en.wikipedia.org/wiki/Scanning_electron_microscope

    An account of the early history of scanning electron microscopy has been presented by McMullan. [2] [3] Although Max Knoll produced a photo with a 50 mm object-field-width showing channeling contrast by the use of an electron beam scanner, [4] it was Manfred von Ardenne who in 1937 invented [5] a microscope with high resolution by scanning a very small raster with a demagnified and finely ...

  3. Cell nucleus - Wikipedia

    en.wikipedia.org/wiki/Cell_nucleus

    A nucleus typically contains between one and ten compact structures called Cajal bodies or coiled bodies (CB), whose diameter measures between 0.2 μm and 2.0 μm depending on the cell type and species. [35] When seen under an electron microscope, they resemble balls of tangled thread [36] and are dense foci of distribution for the protein ...

  4. Transmission electron microscopy - Wikipedia

    en.wikipedia.org/wiki/Transmission_electron...

    A TEM image of a cluster of poliovirus.The polio virus is 30 nm in diameter. [1] Operating principle of a transmission electron microscope. Transmission electron microscopy (TEM) is a microscopy technique in which a beam of electrons is transmitted through a specimen to form an image.

  5. Nucleolus - Wikipedia

    en.wikipedia.org/wiki/Nucleolus

    Electron micrograph of part of a HeLa cell. The image is a screen capture from this movie, which shows a Z-stack of the cell. In ribosome biogenesis, two of the three eukaryotic RNA polymerases (Pol I and Pol III) are required, and these function in a coordinated manner.

  6. Transmission electron microscopy DNA sequencing - Wikipedia

    en.wikipedia.org/wiki/Transmission_electron...

    Transmission electron microscopy DNA sequencing is a single-molecule sequencing technology that uses transmission electron microscopy techniques. The method was conceived and developed in the 1960s and 70s, [ 1 ] but lost favor when the extent of damage to the sample was recognized.

  7. Nuclear envelope - Wikipedia

    en.wikipedia.org/wiki/Nuclear_envelope

    The actual shape of the nuclear envelope is irregular. It has invaginations and protrusions and can be observed with an electron microscope. A volumetric surface render (red) of the nuclear envelope of one HeLa cell. The cell was observed in 300 slices of electron microscopy, the nuclear envelope was automatically segmented and rendered. One ...

  8. Nuclear pore complex - Wikipedia

    en.wikipedia.org/wiki/Nuclear_pore_complex

    The nuclear pore complex (NPC) is a crucial cellular structure with a diameter of approximately 120 nanometers in vertebrates. Its channel varies from 5.2 nanometers in humans [14] to 10.7 nm in the frog Xenopus laevis, with a depth of roughly 45 nm. [15]

  9. Annular dark-field imaging - Wikipedia

    en.wikipedia.org/wiki/Annular_dark-field_imaging

    Annular dark-field imaging is a method of mapping samples in a scanning transmission electron microscope (STEM). These images are formed by collecting scattered electrons with an annular dark-field detector. [1] Conventional TEM dark-field imaging uses an objective aperture to only collect scattered electrons that pass through.