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In a 2015 articles in the Journal of Urology, Thompson reported multi-parametric MRI detection of significant prostate cancer had sensitivity of 96%, specificity of 36%, negative predictive value and positive predictive values of 92% and 52%; when PI-RADS was incorporated into a multivariate analysis (PSA, digital rectal exam, prostate volume ...
Alan Wayne Partin (March 16, 1961 – March 28, 2023) was an American prostate surgeon and researcher. He was the Jakurski Family Director of the Brady Urological Institute, Urologist-In-Chief of Johns Hopkins School of Medicine, and professor of urology, Pathology, and Oncology.
The Gleason grading system is used to help evaluate the prognosis of men with prostate cancer using samples from a prostate biopsy. Together with other parameters, it is incorporated into a strategy of prostate cancer staging which predicts prognosis and helps guide therapy. A Gleason score is given to prostate cancer based upon its microscopic ...
SimBioSys anticipates FDA clearance for its breast cancer surgical planning tool in late 2023 with an expansion to other solid tumors to follow. Validation to lung and prostate cancer is already underway. While awaiting FDA approval, SimBioSys is commercializing the technology for use in patient education and drug development.
Prostate cancer antigen 3 is a urine test that detects the overexpression of the PCA3 gene, an indicator of prostate cancer. [32] [46] [47] [44] ConfirmMDx is performed on tissue taken during a prostate biopsy. The test identifies men with clinically significant prostate cancer who would benefit from further testing and treatment.
He also made significant contributions by discovering novel pathway-targeted interventions and developing novel prediction models for therapeutic response. Recent research interests are aligned with the field of public health, prevention medicine, implementation science and comparative effectiveness research in academic and community-based ...
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For example, Sreekumar et al reported that the level of sarcosine, which is a derivative of glycine, in the urine of men is correlated with metastasis of prostate cancer. [ 11 ] References