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Pharmacology can be applied within clinical sciences. Clinical pharmacology is the application of pharmacological methods and principles in the study of drugs in humans. [21] An example of this is posology, which is the study of dosage of medicines. [22] Pharmacology is closely related to toxicology.
An example of a pharmacophore model. In medicinal chemistry and molecular biology, a pharmacophore is an abstract description of molecular features that are necessary for molecular recognition of a ligand by a biological macromolecule.
In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect. [2] A mechanism of action usually includes mention of the specific molecular targets to which the drug binds, such as an enzyme or receptor . [ 3 ]
The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection). Pharmacodynamics and pharmacokinetics are the main branches of pharmacology , being itself a topic of biology interested in the study of the interactions of both endogenous and exogenous chemical ...
At the biological interface, medicinal chemistry combines to form a set of highly interdisciplinary sciences, setting its organic, physical, and computational emphases alongside biological areas such as biochemistry, molecular biology, pharmacognosy and pharmacology, toxicology and veterinary and human medicine; these, with project management ...
Molecular medicine is a new scientific discipline in European universities. [11] Combining contemporary medical studies with the field of biochemistry , it offers a bridge between the two subjects. At present only a handful of universities offer the course to undergraduates .
Examples of common classes of biological targets are proteins and nucleic acids. The definition is context-dependent, and can refer to the biological target of a pharmacologically active drug compound , the receptor target of a hormone (like insulin ), or some other target of an external stimulus.
Molecular Pharmacology is a peer-reviewed scientific journal published by the American Society for Pharmacology and Experimental Therapeutics since 1965. It is indexed in MEDLINE, Meta, Scopus, and other databases. [1] [2] According to the Journal Citation Reports, the journal received a 2017 impact factor of 3.987. [3]