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  2. Dabigatran - Wikipedia

    en.wikipedia.org/wiki/Dabigatran

    Dabigatran, sold under the brand name Pradaxa among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. [ 6 ] [ 7 ] Specifically it is used to prevent blood clots following hip or knee replacement and in those with a history of prior clots. [ 6 ]

  3. Direct thrombin inhibitor - Wikipedia

    en.wikipedia.org/wiki/Direct_thrombin_inhibitor

    Dabigatran is an oral direct thrombin inhibitor. Dabigatran (Pradaxa) was found to be noninferior to Warfarin in prevention of ischemic stroke, as well as intracranial hemorrhage risk and overall mortality for non-valvular atrial fibrillation according to the RE-LY trial. [9]

  4. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Factors considered before deciding on whether warfarin or a DOAC or which direct factor Xa inhibitor is used, include: the presence or absence of valvular heart disease, state of kidney function, the risk of stroke and the risk of bleeding. [8]

  5. Discovery and development of direct thrombin inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Dabigatran etexilate was approved in Canada and Europe in 2008 for the prevention of VTE in patients undergoing hip- and knee surgery. In October 2010 the US FDA approved dabigatran etexilate for the prevention of stroke in patients with atrial fibrillation (AF).

  6. The No. 1 Pre-Breakfast Habit for Dementia Prevention - AOL

    www.aol.com/lifestyle/treat-patients-alzheimer...

    A 2016 study suggests that consuming coffee and caffeine is “associated with prevention of cognitive decline” and a reduced risk of Alzheimer’s disease, stroke and Parkinson’s disease. Get ...

  7. Deep vein thrombosis - Wikipedia

    en.wikipedia.org/wiki/Deep_vein_thrombosis

    Warfarin, dabigatran, and edoxaban require the use of a parenteral anticoagulant to initiate oral anticoagulant therapy. [ 19 ] [ 125 ] When warfarin is initiated for VTE treatment, a 5-day minimum of a parenteral anticoagulant [ j ] together with warfarin is given, which is followed by warfarin-only therapy.

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