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Bromism is the syndrome which results from the long-term consumption of bromine, usually through bromine-based sedatives such as potassium bromide and lithium bromide. Bromism was once a very common disorder, being responsible for 5 to 10% of psychiatric hospital admissions, but is now uncommon since bromide was withdrawn from clinical use in ...
However, bromine is beneficial for human eosinophils, [10] and is an essential trace element for collagen development in all animals. [11] Hundreds of known organobromine compounds are generated by terrestrial and marine plants and animals, and some serve important biological roles. [12]
The half-life of bromide in the human body (12 days) is long compared with many pharmaceuticals, making dosing challenging to adjust. (A new dose may require several months to reach equilibrium.) Bromide ion concentrations in the cerebrospinal fluid are about 30% of those in blood and are strongly influenced by the body's chloride intake and ...
Metal toxicity or metal poisoning is the toxic effect of certain metals in certain forms and doses on life.Some metals are toxic when they form poisonous soluble compounds. . Certain metals have no biological role, i.e. are not essential minerals, or are toxic when in a certain for
Hexabromocyclododecane (HBCD or HBCDD) is a ring consisting of twelve carbon atoms with six bromine atoms tied to the ring. The commercially used HBCD is in fact a mixture of different isomers. HBCD is toxic to water-living organisms. The UNEP Stockholm Convention has listed HBCD for elimination, but allowing a temporary exemption for the use ...
Median lethal (LD 50) doses of theobromine have only been published for cats, dogs, rats, and mice; these differ by a factor of 6 across species.[6]Serious poisoning happens more frequently in domestic animals, which metabolize theobromine much more slowly than humans, [7] and can easily consume enough chocolate to cause poisoning.
Brominated vegetable oil (BVO) is a complex mixture of plant-derived triglycerides that have been modified by atoms of the element bromine bonded to the fat molecules. . Brominated vegetable oil has been used to help emulsify citrus-flavored beverages, especially soft drinks, preventing them from separating during dist
Even without dietary intake, theobromine may occur in the body as it is a product of the human metabolism of caffeine, which is metabolised in the liver into 12% theobromine, 4% theophylline, and 84% paraxanthine. [26] In the liver, theobromine is metabolized into xanthine and subsequently into methyluric acid. [27]