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Serial quantitative blood tests may be done, usually 48 hours apart, and interpreted based on the knowledge that hCG in a viable normal pregnancy rises rapidly in early pregnancy. For example, for a starting hCG level of 1,500 mIU/ml or less, the hCG of continuing, normal pregnancy will increase at least 49% in 48 hours.
Human chorionic gonadotropin is a glycoprotein composed of 237 amino acids with a molecular mass of 36.7 kDa, approximately 14.5kDa αhCG and 22.2kDa βhCG. [4]It is heterodimeric, with an α (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and a β (beta) subunit that is unique to hCG.
Blood and urine tests can detect pregnancy by 11 and 14 days, respectively, after fertilization. [77] [78] Blood pregnancy tests are more sensitive than urine tests (giving fewer false negatives). [79] Home pregnancy tests are urine tests, and normally detect a pregnancy 12 to 15 days after fertilization. [80]
A new blood test can be performed in a pregnant person’s first trimester to help assess their risk of developing preeclampsia, a potentially life-threatening pregnancy complication.
Pregnancy tests fall into two categories: at-home urine tests and the in-office blood test. At-home urine tests have different thresholds for the level of hCG they’re looking for, Dr. Ahmad says.
Urine-based pregnancy tests detect hCG in the urine, while blood-based pregnancy tests measure the level of hCG in the blood. [5] The presence of hCG in a woman's body indicates that a fertilized egg has implanted in the uterus and the placenta has started to form. 10 days after fertilization, significant hCG can be detected from woman's blood ...
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