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Pustulosis palmaris et plantaris is a chronic recurrent pustular dermatosis (that is, a pustulosis or pustular psoriasis) localized on the palms and soles only, characterized histologically by intraepidermal pustules filled with neutrophils. [2]: 411, 628 [3]: 204 It can occur as part of the SAPHO syndrome. [4]
Pustular psoriasis can be localized, commonly to the hands and feet (palmoplantar pustulosis), or generalized with widespread patches occurring randomly on any part of the body. Acrodermatitis continua is a form of localized psoriasis limited to the fingers and toes that may spread to the hands and feet. [ 4 ]
Pustulosis is highly inflammatory skin condition resulting in large fluid-filled blister-like areas - pustules. Pustulosis typically occurs on the palms of the hands and/or the soles of the feet. The skin of these areas peels and flakes . [1] This condition—also referred to as "palmo-plantar pustulosis"—is a feature of pustular psoriasis.
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Psoriasis is a common, chronic, and recurrent inflammatory disease of the skin characterized by circumscribed, erythematous, dry, scaling plaques. [97] [98] [99] Psoriasis vulgaris. Annular pustular psoriasis; Drug-induced psoriasis; Exanthematic pustular psoriasis; Generalized pustular psoriasis (pustular psoriasis of von Zumbusch)
Localized pustular psoriasis presents as two distinct conditions that must be considered separate from generalized psoriasis, and without systemic symptoms, these two distinct varieties being pustulosis palmaris et plantaris and acrodermatitis continua. [1]: 411
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