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Still, trazodone is often helpful for geriatric patients with depression who have severe agitation and insomnia. [27] Trazodone is usually used at a dosage of 150 to 300 mg/day for the treatment of depression. [17] [13] Lower doses have also been used to augment other antidepressants or when initiating therapy.
This is a list of adverse effects of the antidepressant trazodone, sorted by frequency of occurrence. [1] [2] [3] ... Insomnia; Dream disorder; Disorientation ...
Used off-label for anxiety, Alzheimer's disease, bulimia, fibromyalgia and PTSD, trazodone is also commonly used to treat insomnia at a lower dosage than for depression. Trazodone has even been ...
Chemical structure of the serotonin antagonist and reuptake inhibitor trazodone. Serotonin antagonist and reuptake inhibitors ( SARIs ) are a class of drugs used mainly as antidepressants , but also as anxiolytics and hypnotics .
Desyrel – an atypical antidepressant used to treat depression and insomnia; Desoxyn (methamphetamine hydrochloride) – used to treat attention deficit hyperactivity disorder and exogenous obesity; Dexedrine (dextroamphetamine sulfate) – used to treat attention deficit hyperactivity disorder and narcolepsy
The consensus is to reduce dosage gradually over several weeks, e.g. 4 or more weeks for diazepam doses over 30 mg/day, [1] with the rate determined by the person's ability to tolerate symptoms. [120] The recommended reduction rates range from 50% of the initial dose every week or so, [121] to 10–25% of the daily dose every 2 weeks. [120]
Insomnia can be difficult to treat in these individuals because many of the traditional sleep aids (e.g., benzodiazepine receptor agonists and barbiturate receptor agonists) work via a GABA A receptor mechanism and are cross-tolerant with alcohol. However, trazodone is not cross-tolerant with alcohol.
The effects saturate with low levels of exposure, so that the effects of low-dose exposure are similar to high-dose effects. Continued use of nicotine could also lead to DNA damage and thereby ...
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