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  2. Native American disease and epidemics - Wikipedia

    en.wikipedia.org/wiki/Native_American_disease...

    Aside from that, most of the major infectious diseases known today originated in the Old World (Africa, Asia, and Europe). The American era of limited infectious disease ended with the arrival of Europeans in the Americas and the Columbian exchange of microorganisms, including those that cause human diseases

  3. History of syphilis - Wikipedia

    en.wikipedia.org/wiki/History_of_syphilis

    The history of syphilis has been well studied, but the exact origin of the disease remains unknown. [3] It appears to have originated in both Africa and America. [4] [5] As such, there are two primary hypotheses: one proposes that syphilis was carried to Europe from the Americas by the crew(s) of Christopher Columbus as a byproduct of the Columbian exchange, while the other proposes that ...

  4. Disease in colonial America - Wikipedia

    en.wikipedia.org/wiki/Disease_in_colonial_America

    Disease in colonial America that afflicted the early immigrant settlers was a dangerous threat to life. Some of the diseases were new and treatments were ineffective. Some of the diseases were new and treatments were ineffective.

  5. Columbian exchange - Wikipedia

    en.wikipedia.org/wiki/Columbian_exchange

    The Columbian exchange, also known as the Columbian interchange, was the widespread transfer of plants, animals, and diseases between the New World (the Americas) in the Western Hemisphere, and the Old World (Afro-Eurasia) in the Eastern Hemisphere, from the late 15th century on.

  6. Influx of disease in the Caribbean - Wikipedia

    en.wikipedia.org/wiki/Influx_of_disease_in_the...

    The first European contact in 1492 started an influx of communicable diseases into the Caribbean. [1] Diseases originating in the Old World (Afro-Eurasia) came to the New World (the Americas) for the first time, resulting in demographic and sociopolitical changes due to the Columbian Exchange from the late 15th century onwards. [1]

  7. List of epidemics and pandemics - Wikipedia

    en.wikipedia.org/wiki/List_of_epidemics_and...

    Widespread non-communicable diseases such as cardiovascular disease and cancer are not included. An epidemic is the rapid spread of disease to a large number of people in a given population within a short period of time; in meningococcal infections , an attack rate in excess of 15 cases per 100,000 people for two consecutive weeks is considered ...

  8. List of diseases eliminated from the United States - Wikipedia

    en.wikipedia.org/wiki/List_of_diseases...

    This is a list of diseases known (or declared) to have been eliminated from the United States, either permanently or at one time. (" Elimination " is the preferred term for "regional eradication" of a disease; the term " eradication " is reserved for the reduction of an infectious disease's global prevalence to zero.)

  9. Indigenous peoples of the Americas - Wikipedia

    en.wikipedia.org/wiki/Indigenous_peoples_of_the...

    Like Indigenous peoples, these African people, newly exposed to European diseases, lacked any inherited resistance to the diseases of Europe. In 1520, an African who had been infected with smallpox had arrived in Yucatán. By 1558, the disease had spread throughout South America and had arrived at the Plata basin. [120]