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The efficacy of arsenic trioxide has also been demonstrated in the treatment of multiple myeloma, in combination with ascorbic acid [56] and bortezomib. [ 57 ] Animal studies have shown that the drug also affects ovarian, [ 58 ] liver, stomach, [ 59 ] prostate, and breast cancers, [ 60 ] as well as gliomas [ 61 ] and pancreatic cancer (in ...
Arsenic trioxide is indicated in combination with tretinoin for treatment of adults with newly-diagnosed low-risk acute promyelocytic leukemia whose acute promyelocytic leukemia is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression; and for induction of remission and consolidation in patients with acute promyelocytic leukemia who are refractory to, or ...
Arsenic trioxide (As 2 O 3) inhibits cell growth and induces apoptosis (programmed cell death) in certain types of cancer cells, [23] which are normally immortal and can multiply without limit. In combination with all-trans retinoic acid , it is FDA-approved as first-line treatment for promyelocytic leukemia .
In homeopathy, arsenicum album (Arsenic. alb. ) is a solution prepared by diluting aqueous arsenic trioxide generally until there is little amounts of Arsenic remaining in individual doses. It is used by homeopaths to treat a range of symptoms that include digestive disorders and, as an application of the Law of Similars , has been suggested by ...
In chemistry, an arsenite is a chemical compound containing an arsenic oxyanion where arsenic has oxidation state +3. Note that in fields that commonly deal with groundwater chemistry, arsenite is used generically to identify soluble As III anions. IUPAC have recommended that arsenite compounds are to be named as arsenate(III), for example ...
Arsenic trioxide powder.. Compounds of arsenic resemble in some respects those of phosphorus which occupies the same group (column) of the periodic table.The most common oxidation states for arsenic are: −3 in the arsenides, which are alloy-like intermetallic compounds, +3 in the arsenites, and +5 in the arsenates and most organoarsenic compounds.
Induction chemotherapy is the first line treatment of cancer with a chemotherapeutic drug. This type of chemotherapy is used for curative intent. [1] [6]: 55–59 Combined modality chemotherapy is the use of drugs with other cancer treatments, such as surgery, radiation therapy, or hyperthermia therapy.
It burns in oxygen to form arsenic trioxide and arsenic pentoxide, which have the same structure as the more well-known phosphorus compounds, and in fluorine to give arsenic pentafluoride. [31] Arsenic makes arsenic acid with concentrated nitric acid , arsenous acid with dilute nitric acid, and arsenic trioxide with concentrated sulfuric acid ...