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Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...
The symptoms of Cushing's disease are similar to those seen in other causes of Cushing's syndrome. [5] Patients with Cushing's disease usually present with one or more signs and symptoms secondary to the presence of excess cortisol or ACTH. [6] Although uncommon, some patients with Cushing's disease have large pituitary tumors (macroadenomas).
[35] [36] Cushing's syndrome can either be exogenous or endogenous, depending on whether it is caused by an external or internal source, respectively. [37] The intake of glucocorticoids, a type of corticosteroid, is a common cause for the development of exogenous Cushing's syndrome. Endogenous Cushing's syndrome can occur when the body produces ...
Inferior petrosal sinus sampling (or IPSS), is a diagnostic medical procedure used to determine whether excess adrenocorticotropic hormone (ACTH) is coming from the pituitary gland (usually a pituitary adenoma causing Cushing's disease) or from a source outside the pituitary (a rare tumor causing ectopic ACTH syndrome).
This is a shortened version of the third chapter of the ICD-9: Endocrine, Nutritional and Metabolic Diseases, and Immunity Disorders.It covers ICD codes 240 to 279.The full chapter can be found on pages 145 to 165 of Volume 1, which contains all (sub)categories of the ICD-9.
These include renal artery stenosis and tumors (generally nonmalignant) of the adrenal glands, e.g., Conn's syndrome (primary hyperaldosteronism). Cushing's syndrome can also lead to hypokalemia due to excess cortisol binding the Na + /K + pump and acting like aldosterone. Hypertension and hypokalemia can also be seen with a deficiency of the ...
There are a number of causes of hypercalciuria including genetic (idiopathic), primary hyperparathyroidism, immobilization, pagets disease, Multiple Myeloma, Calcium excess, Vitamin D excess/increased sensitivity, drug-induced hypercalciuria, sarcoidosis, hyperthyroidism, Cushing's disease, and renal tubular acidosis. [1] [4]
Pseudo-Cushing's syndrome or non-neoplastic hypercortisolism is a medical condition in which patients display the signs, symptoms, and abnormal cortisol levels seen in Cushing's syndrome. However, pseudo-Cushing's syndrome is not caused by a problem with the hypothalamic-pituitary-adrenal axis as Cushing's is; it is mainly an idiopathic ...
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