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Phenylbiguanide (PBG) is a 5-HT3 agonist used to study the role of 5-HT3 receptors in the central nervous system. [1] It has been found to trigger dopamine release in the nucleus accumbens of rats. [ 2 ]
The mechanism of action of biguanides is not fully understood, and many mechanisms have been proposed for metformin. [citation needed]Biguanides do not affect the output of insulin, unlike other hypoglycemic agents such as sulfonylureas and meglitinides.
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Indonesia and South Korea's diplomatic relationship commenced in the mid-20th century. Indonesia formally acknowledged the Republic of Korea on September 17, 1966, and they officially established diplomatic ties on September 18, 1973. This era marked the onset of a durable partnership that has progressively developed over the years.
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The first K-pop concert in Indonesia was held in 2010 during Indonesia-Korea Week, where the group that attended was SHINee. Seeing the potential and enthusiasm of fans at that time, SM Entertainment brought back their artists 2 years later, in 2012 SMTown Concert succeeded filling Gelora Bung Karno in Jakarta with 50,000 people.
The Indonesia–Korea Comprehensive Economic Partnership Agreement is a bilateral agreement signed between Indonesia and South Korea. Negotiated since 2012, it was signed in December 2020 and came into effect on 1 January 2023.
Located in the transition area of Asia and Australia zone, the national park has many unique animals collection, such as Sulawesi moor macaque (Macaca maura), the red-knobbed hornbill (Aceros cassidix, Penelopides exarhatus), cuscus (Strigocuscus celebensis), Sulawesi palm civet (Macrogalidia musschenbroekii), bat, and pot-bellied boar (Sus scrofa vittatus).