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Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. [4] [5] These areas are red, pink, or purple, dry, itchy, and scaly.[8] [3] Psoriasis varies in severity from small localized patches to complete body coverage. [3]
Apremilast. Apremilast, sold under the brand name Otezla among others, is a medication for the treatment of certain types of psoriasis and psoriatic arthritis. The drug acts as a selective inhibitor of the enzyme phosphodiesterase 4 (PDE4) and inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells. [7]
Psoriatic erythroderma represents a form of psoriasis that affects all body sites, including the face, hands, feet, nails, trunk, and extremities. [1]: 410–411 [2]: 195 This specific form of psoriasis affects 3 percent of persons diagnosed with psoriasis. [3] First-line treatments for psoriatic erythroderma include immunosuppressive ...
Psoriatic arthritis (PsA) is a long-term inflammatory arthritis that occurs in people affected by the autoimmune disease psoriasis. [1][2] The classic feature of psoriatic arthritis is swelling of entire fingers and toes with a sausage-like appearance ("sausage digit"). [3]
Psoriasis Area and Severity Index. Psoriasis Area and Severity Index (PASI) is the most widely used tool for the measurement of severity of psoriasis. PASI combines the assessment of the severity of lesions and the area affected into a single score in the range 0 (no disease) to 72 (maximal disease). [1]
For example, if you require 2,500 calories per day to maintain your weight, you would need to consume less than 2,500 calories per day to create a deficit. This can be done by reducing your ...
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