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2. Leucine - Wikipedia

   en.wikipedia.org/wiki/Leucine

   Leucine (symbol Leu or L) [3] is an essential amino acid that is used in the biosynthesis of proteins.Leucine is an α-amino acid, meaning it contains an α-amino group (which is in the protonated −NH 3 + form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO − form under biological conditions), and a side chain isobutyl group, making it a non ...

3. Microcystin-LR - Wikipedia

   en.wikipedia.org/wiki/Microcystin-LR

   Microcystin-LR had effects on all animals, not only the domestic animals from swimming in a river of drinking water with cyanobacteria blooms. Symptoms in domestic animal poisoning include diarrhea, vomiting, weakness, recumbency and are fatal in most cases [12] [13] Mircocystin-LR is toxic for all animals, including the animals consumed by humans.

4. Gabapentin - Wikipedia

   en.wikipedia.org/wiki/Gabapentin

   The endogenous α-amino acids L-leucine and L-isoleucine, which resemble gabapentin in chemical structure, bind α 2 δ with similar affinity to gabapentin and are present in human cerebrospinal fluid at micromolar concentrations. [84] They may be the endogenous ligands of the α 2 δ subunit, and they competitively antagonize the effects of ...

5. Maple syrup urine disease - Wikipedia

   en.wikipedia.org/wiki/Maple_syrup_urine_disease

   Medical genetics, Dietetics. Maple syrup urine disease (MSUD) is a rare, inherited metabolic disorder that affects the body’s ability to metabolize amino acids due to a deficiency in the activity of the branched-chain alpha-ketoacid dehydrogenase (BCKAD) complex. [3] It particularly affects the metabolism of amino acids- leucine, isoleucine ...

6. α-Ketoisocaproic acid - Wikipedia

   en.wikipedia.org/wiki/Α-Ketoisocaproic_acid

   α-Ketoisocaproic acid (α-KIC), also known as 4-methyl-2-oxovaleric acid, and its conjugate base and carboxylate, α-ketoisocaproate, are metabolic intermediates in the metabolic pathway for L -leucine. [2] Leucine is an essential amino acid, and its degradation is critical for many biological duties. [3] α-KIC is produced in one of the first ...

7. Saunas have health benefits, but overuse is linked to ... - AOL

   www.aol.com/news/saunas-health-benefits-overuse...

   The risks include dehydration, heat exhaustion and stroke, according to Jeffy. Make sure to drink water to keep yourself hydrated while in a sauna. To avoid potential dehydration, bring a bottle ...

8. Propionic acidemia - Wikipedia

   en.wikipedia.org/wiki/Propionic_acidemia

   Propionic acidemia, also known as propionic aciduria or propionyl-CoA carboxylase deficiency (PCC deficiency), [1] is a rare autosomal recessive metabolic disorder, classified as a branched-chain organic acidemia. [2][3] The disorder presents in the early neonatal period with poor feeding, vomiting, lethargy, and lack of muscle tone. [4]

9. Leucyl aminopeptidase - Wikipedia

   en.wikipedia.org/wiki/Leucyl_aminopeptidase

   Leucyl aminopeptidases (EC 3.4.11.1, leucine aminopeptidase, LAPs, leucyl peptidase, peptidase S, cytosol aminopeptidase, cathepsin III, L-leucine aminopeptidase, leucinaminopeptidase, leucinamide aminopeptidase, FTBL proteins, proteinates FTBL, aminopeptidase II, aminopeptidase III, aminopeptidase I) are enzymes that preferentially catalyze the hydrolysis of leucine residues at the N-terminus ...