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Melatonin is the most popular over-the-counter sleep remedy in the United States, resulting in sales in excess of US$400 million during 2017. [70] In 2022, it was the 217th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [26] [27]
Melatonin supplements for sleep come with side effects and their use may raise safety concerns, experts say. There's little evidence they help with insomnia.
Melatonin in the form of prolonged release (trade name Circadin) was approved in 2007 in Europe (EU) for use as a short-term treatment, in patients 55 years and older, for primary insomnia. [59] Tasimelteon (trade name Hetlioz) received FDA approval in January 2014 for blind persons diagnosed with non-24. [60]
Melatonin is used both as a prescription medication and an over-the-counter dietary supplement for the management of sleep disorders, including insomnia and various circadian rhythm sleep disorders such as delayed sleep phase disorder, jet lag disorder, and shift work sleep disorder. [55]
Over-the-counter sleep supplements are a different story. It’s important not to rely on products like ZzzQuil, Benadryl, melatonin gummies, or Advil PM, Wang says. “If you’re sick and need ...
Is melatonin or ashwagandha safer for sleep? Since sleep medications can cause significant problems, Teitelbaum likes to start with natural, safer alternatives like melatonin and ashwagandha.
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