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Signal enhancement by extravascular water protons, or SEEP, is a contrast mechanism for functional magnetic resonance imaging (fMRI), which is an alternative to the more commonly employed BOLD (blood-oxygen-level dependent) contrast. This mechanism for image contrast changes corresponding to changes in neuronal activity was first proposed by Dr ...
The typical discarding of the low-frequency signals in BOLD-contrast imaging came into question in 1995, when it was observed that the "noise" in the area of the brain that controls right-hand movement fluctuated in unison with similar activity in the area on the opposite side of the brain associated with left-hand movement. [1] BOLD-contrast ...
The primary form of fMRI uses the blood-oxygen-level dependent (BOLD) contrast, [4] discovered by Seiji Ogawa in 1990. This is a type of specialized brain and body scan used to map neural activity in the brain or spinal cord of humans or other animals by imaging the change in blood flow ( hemodynamic response ) related to energy use by brain ...
A detailed diagram depicting the global water cycle. The direction of movement of water between reservoirs tends towards upwards movement through evapotranspiration and downward movement through gravity. The diagram also shows how human water use impacts where water is stored and how it moves. [1]
The mechanism of antiporter transport involves several key steps and a series of conformational changes that are dictated by the structural element described above: [7] The substrate binds to its specific binding site on the extracellular side of the plasma membrane, forming a temporary substrate-bound open form of the antiporter.
Protons tunnel across a series of hydrogen bonds between hydronium ions and water molecules.. The Grotthuss mechanism (also known as proton jumping) is a model for the process by which an 'excess' proton or proton defect diffuses through the hydrogen bond network of water molecules or other hydrogen-bonded liquids through the formation and concomitant cleavage of covalent bonds involving ...
In physics, physical chemistry and engineering, fluid dynamics is a subdiscipline of fluid mechanics that describes the flow of fluids – liquids and gases.It has several subdisciplines, including aerodynamics (the study of air and other gases in motion) and hydrodynamics (the study of water and other liquids in motion).
A contrast CT of a pulmonary artery with an embolism. Note the contrast between the embolism (center, grey) and the surrounding blood (black). This is because the blood contains a negative radiocontrast agent; without the radiocontrast, the blood and the embolism may be indistinguishable.