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Allele. An allele[1], or allelomorph, is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule. [2] Alleles can differ at a single position through single nucleotide polymorphisms (SNP), [3] but they can also have insertions and deletions of up to several thousand base pairs. [4]
Allele frequency, or gene frequency, is the relative frequency of an allele (variant of a gene) at a particular locus in a population, expressed as a fraction or percentage. [1] Specifically, it is the fraction of all chromosomes in the population that carry that allele over the total population or sample size.
Evolutionary biology. Genetic drift, also known as random genetic drift, allelic drift or the Wright effect, [1] is the change in the frequency of an existing gene variant (allele) in a population due to random chance. [2] Genetic drift may cause gene variants to disappear completely and thereby reduce genetic variation. [3]
Category. v. t. e. The genotype of an organism is its complete set of genetic material. [1] Genotype can also be used to refer to the alleles or variants an individual carries in a particular gene or genetic location. [2] The number of alleles an individual can have in a specific gene depends on the number of copies of each chromosome found in ...
If the sequence of the nucleotides in a gene changes, the sequence of the amino acids in the protein it produces may also change—if part of a gene is deleted, the protein produced is shorter and may not work anymore. [6] This is the reason why different alleles of a gene can have different effects on an organism.
A gene can acquire mutations in its sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a gene, which may cause different phenotypical traits. [4] Genes evolve due to natural selection or survival of the fittest and genetic drift of the alleles.
Genetic drift is a cause of allelic frequency change within populations of a species. Alleles are different variations of specific genes. They determine things like hair colour, skin tone, eye colour and blood type; in other words, all the genetic traits that vary between individuals. Genetic drift does not introduce new alleles to a population ...
Allele age (or mutation age) is the amount of time elapsed since an allele first appeared due to mutation. Estimating the time at which a certain allele appeared allows researchers to infer patterns of human migration, disease, and natural selection. Allele age can be estimated based on (1) the frequency of the allele in a population and (2 ...