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Metered-dose Inhaler. A metered-dose inhaler (MDI) is a device that delivers a specific amount of medication to the lungs in the form of a short burst of aerosolized medicine that is usually self-administered by the patient via inhalation. It is the most commonly used delivery system for treating asthma, chronic obstructive pulmonary disease ...
Nicotine replacement therapy (NRT) is a medically approved way to treat people with tobacco use disorder by taking nicotine through means other than tobacco. [ 6 ] It is used to help with quitting smoking or stopping chewing tobacco. [ 1 ][ 7 ] It increases the chance of quitting tobacco smoking by about 55%. [ 8 ]
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
Website. nicorette.com. Nicorette is the brand name of a number of products for nicotine replacement therapy (NRT) that contain nicotine polacrilex. Developed in the late 1970s in Sweden by AB Leo [sv] in the form of a chewing gum, Nicorette was the first nicotine replacement product on the market. [1]
Nicotine-free e-cigarette vapor did not have this effect. [149] The health effects of passive exposure to e-cigarettes with no nicotine, as well as the extent of exposure to these products, have just begun to be studied. [146] E-cigarettes that do not contain nicotine generate hazardous vapors [150] and could still present a risk to non-users ...
An electronic cigarette(e-cigarette), or vape,[note 1][1]is a vaporizerdevice that simulates tobacco smoking. It consists of an atomizer, a power source such as a battery, and a container such as a cartridge or tank. Instead of smoke, the user inhales vapor.[2]
Nicotine is a hygroscopic, colorless to yellow-brown, oily liquid, that is readily soluble in alcohol, ether or light petroleum. It is miscible with water in its neutral amine base form between 60 °C and 210 °C. It is a dibasic nitrogenous base, having K b1 =1×10 −6, K b2 =1×10 −11. [ 163 ]
Nicotine dependence[notes 2] is a state of substance dependence on nicotine. [3] It is a chronic, relapsing disease characterized by a compulsive craving to use the drug despite social consequences, loss of control over drug intake, and the emergence of withdrawal symptoms. [7] Tolerance is another component of drug dependence. [8]