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Cerebral circulation is the movement of blood through a network of cerebral arteries and veins supplying the brain. The rate of cerebral blood flow in an adult human is typically 750 milliliters per minute, or about 15% of cardiac output. Arteries deliver oxygenated blood, glucose and other nutrients to the brain.
The canonical haemodynamic response function (HRF). The spike indicates a brief intense period of neuron stimulation, which requires increased blood and nutrient flow. As the needs of the neuronal activity are met, blood flow returns to homeostatic levels. In haemodynamics, the body must respond to physical activities, external temperature, and ...
Cerebral perfusion pressure. Cerebral perfusion pressure, or CPP, is the net pressure gradient causing cerebral blood flow to the brain (brain perfusion). It must be maintained within narrow limits because too little pressure could cause brain tissue to become ischemic (having inadequate blood flow), and too much could raise intracranial ...
Penumbra (medicine) In pathology and anatomy the penumbra is the area surrounding an ischemic event such as thrombotic or embolic stroke. Immediately following the event, blood flow and therefore oxygen transport is reduced locally, leading to hypoxia of the cells near the location of the original insult. This can lead to hypoxic cell death ...
Cerebral edema is excess accumulation of fluid (edema) in the intracellular or extracellular spaces of the brain. [ 1 ] This typically causes impaired nerve function, increased pressure within the skull, and can eventually lead to direct compression of brain tissue and blood vessels. [ 1 ] Symptoms vary based on the location and extent of edema ...
Cerebral autoregulation. Cerebral autoregulation is a process in mammals that aims to maintain adequate and stable cerebral blood flow. While most systems of the body show some degree of autoregulation, [1] the brain is very sensitive to over- and underperfusion. Cerebral autoregulation plays an important role in maintaining an appropriate ...
The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head (cephalization), usually near organs for special senses such as vision, hearing and olfaction. Being the most specialized organ, it is responsible for receiving ...
The cerebrospinal fluid circulates in the subarachnoid space around the brain and spinal cord, and in the ventricles of the brain. Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates. CSF is produced by specialised ependymal cells in the choroid plexus of ...