Search results
Results from the WOW.Com Content Network
The term "biguanidine" often refers specifically to a class of drugs that function as oral antihyperglycemic drugs used for diabetes mellitus or prediabetes treatment. [4] Examples include: Metformin - widely used in treatment of diabetes mellitus type 2; Phenformin - withdrawn from the market in most countries due to toxic effects
The split and pool synthesis was first applied to prepare peptide libraries on solid support. The synthesis was realized in a home-made manual device shown in the figure. The device has a tube with 20 holes to which reaction vessels could be attached. One end of the tube is linked to a waste container and a water pump.
The commercial route involves a two step process starting with the reaction of dicyandiamide with ammonium salts. Via the intermediacy of biguanidine, this ammonolysis step affords salts of the guanidinium cation (see below). In the second step, the salt is treated with base, such as sodium methoxide. [8]
This page was last edited on 14 May 2014, at 13:04 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply ...
The single purification step at the end of a synthesis allows one or more impurities to be removed, assuming the chemical structure of the offending impurity is known. While the use of solid-supported reagents greatly simplifies the synthesis of compounds, many combinatorial syntheses require multiple steps, each of which still requires some ...
Amateur chemistry or home chemistry is the pursuit of chemistry as a private hobby. [1] Amateur chemistry is usually done with whatever chemicals are available at disposal at the privacy of one's home. It should not be confused with clandestine chemistry, which involves the illicit production of controlled drugs.
Our ability to utilize these skills to create the various sounds needed to communicate effectively is essential to our speech production. Speech is a psychomotor activity. Speech between two people is a conversation - they can be casual, formal, factual, or transactional, and the language structure/ narrative genre employed differs depending ...
Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure ().The technique is extremely useful in current laboratory practice because it provides a rapid and inexpensive access to custom-made oligonucleotides of the desired sequence.