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The term "biguanidine" often refers specifically to a class of drugs that function as oral antihyperglycemic drugs used for diabetes mellitus or prediabetes treatment. [4] Examples include: Metformin - widely used in treatment of diabetes mellitus type 2; Phenformin - withdrawn from the market in most countries due to toxic effects
The commercial route involves a two step process starting with the reaction of dicyandiamide with ammonium salts. Via the intermediacy of biguanidine, this ammonolysis step affords salts of the guanidinium cation (see below). In the second step, the salt is treated with base, such as sodium methoxide. [8]
This page was last edited on 14 May 2014, at 13:04 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply ...
Safe and scalable synthesis of alkynes from aldehydes Recently a safer and more scalable approach has been developed for the synthesis of alkynes from aldehydes. This protocol takes advantage of a stable sulfonyl azide, rather than tosyl azide, for the in situ generation of the Ohira−Bestmann reagent.
Production of antibiotics is a naturally occurring event, that thanks to advances in science can now be replicated and improved upon in laboratory settings. Due to the discovery of penicillin by Alexander Fleming, and the efforts of Florey and Chain in 1938, large-scale, pharmaceutical production of antibiotics has been made possible.
Clarity in speaking is achieved by utilising oral skills. Oral skills strengthen a speakers ability to produce clear and crisp sounds. Using a variety of different oral skills the tonal modulation and articulation of voice. These oral skills include speaking in a moderate pace to produce intelligible speech that can be understood word for word.
Our ability to utilize these skills to create the various sounds needed to communicate effectively is essential to our speech production. Speech is a psychomotor activity. Speech between two people is a conversation - they can be casual, formal, factual, or transactional, and the language structure/ narrative genre employed differs depending ...
Speech processing is the study of speech signals and the processing methods of signals. The signals are usually processed in a digital representation, so speech processing can be regarded as a special case of digital signal processing, applied to speech signals.
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