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The direct toxic effects of alcohol on the heart muscle cells (cardiomyocytes) are considered the primary cause of ACM. [2] Chronic alcohol consumption leads to the accumulation of toxic metabolites, such as acetaldehyde and reactive oxygen species, in the heart muscle cells. [ 2 ]
According to the then-surgeon general's report, a woman who has two drinks a day faces a nearly 22% chance of developing an alcohol-related cancer, compared with a 16.5% risk for a woman drinking ...
If the reaction stops part way through the metabolic pathways, which happens because acetic acid is excreted in the urine after drinking, then not nearly as much energy can be derived from alcohol, indeed, only 215.1 kJ/mol. At the very least, the theoretical limits on energy yield are determined to be −215.1 kJ/mol to −1 325.6 kJ/mol.
The label on the tonic's bottle clearly stated that the recommended dosage (1 tablespoonful taken 4 times a day) was to be taken "...in a 1/2 glass of water after meals and before retiring". However, some pharmacies in dry counties were known to sell it by the shot-glass and at least one bar in New Orleans' French Quarter was known to sell a ...
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The impact of alcohol on weight-gain is contentious: some studies find no effect, [144] others find decreased [145] or increased effect on weight gain. Alcohol use increases the risk of chronic gastritis (stomach inflammation); [3] [146] it is one cause of cirrhosis, hepatitis, and pancreatitis in both its chronic and acute forms.
It has been proposed that for every ten grams of alcohol per day (one beer, wine, or shot of hard alcohol in the U.S. is about 10 to 12 grams of alcohol), the risk of breast cancer may increase ...
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