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Hypocalcemia is a medical condition characterized by low calcium levels in the blood serum. [5] The normal range of blood calcium is typically between 2.1–2.6 mmol/L (8.8–10.7 mg/dL, 4.3–5.2 mEq/L), while levels less than 2.1 mmol/L are defined as hypocalcemic.
Some people suggest that it also may be caused by calcium deficiency, [13] although this is not backed up by research. Leukonychia occurs most commonly in healthy individuals, and is unrelated to any known nutritional or physiological deficiency. [5] When caused by injury the marks will disappear as the nail grows outwards.
Dark nails are associated with B 12 deficiency. Stains of the nail plate (not the nail bed) are associated with smoking and henna use. Splinter hemorrhages (or haemorrhages) are tiny blood clots that tend to run vertically under the nails. Drug-induced nail changes are caused by drug usage which may result in various abnormalities. [6]: 665–6
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Disorders of calcium metabolism occur when the body has too little or too much calcium. The serum level of calcium is closely regulated within a fairly limited range in the human body. In a healthy physiology, extracellular calcium levels are maintained within a tight range through the actions of parathyroid hormone , vitamin D and the calcium ...
Onychomadesis is defined by the nail plate's detachment from the matrix, its continuous connection to the nail bed, and, frequently but not always, shedding. [4] Beau lines are transverse ridges on the nail plates. [5] Onychomadesis might be considered a more severe version of Beau lines. [6]
Healthy term infants go through a physiological nadir of serum calcium levels at 7.5 - 8.5 mg/dL by day 2 of life. Hypocalcemia is a low blood calcium level. A total serum calcium of less than 8 mg/dL (2mmol/L) or ionized calcium less than 1.2 mmol/L in term neonates is defined as hypocalcemia. In preterm infants, it is defined as less than 7mg ...
Beau's lines are deep grooved lines that run from side to side on the fingernail or the toenail. [1] They may look like indentations or ridges in the nail plate. [2]: 657 This condition of the nail was named by a French physician, Joseph Honoré Simon Beau (1806–1865), who first described it in 1846.