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  2. Ciprofloxacin - Wikipedia

    en.wikipedia.org/wiki/Ciprofloxacin

    Ciprofloxacin is 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid. Its empirical formula is C 17 H 18 FN 3 O 3 and its molecular weight is 331.4 g/mol. It is a faintly yellowish to light yellow crystalline substance. [68] Ciprofloxacin hydrochloride is the monohydrochloride monohydrate salt of ciprofloxacin ...

  3. Urinary anti-infective agent - Wikipedia

    en.wikipedia.org/wiki/Urinary_anti-infective_agent

    The choice of urinary anti-infective agents for patients with renal dysfunction is generally similar to that for individuals with normal kidney function. However, in cases where the patient's glomerular filtration rate (GFR) decreases to less than 20 mL/min, drug dosages adjustment is necessary because achieving the desired therapeutic serum ...

  4. Nephrotoxicity - Wikipedia

    en.wikipedia.org/wiki/Nephrotoxicity

    In interventional radiology, a patient's creatinine clearance levels are all checked prior to a procedure. [citation needed] Serum creatinine is another measure of kidney function, which may be more useful clinically when dealing with patients with early kidney disease. Normal creatinine level is between 80 - 120 μmol/L. [citation needed]

  5. Quinolone antibiotic - Wikipedia

    en.wikipedia.org/wiki/Quinolone_antibiotic

    They are used in human and veterinary medicine to treat bacterial infections, as well as in animal husbandry, specifically poultry production. [ 2 ] Nearly all quinolone antibiotics in use are fluoroquinolones , which contain a fluorine atom in their chemical structure and are effective against both Gram-negative and Gram-positive bacteria.

  6. Urinary tract infection - Wikipedia

    en.wikipedia.org/wiki/Urinary_tract_infection

    [7] [18] In women, they are the most common form of bacterial infection. [19] Up to 10% of women have a urinary tract infection in a given year, and half of women have at least one infection at some point in their lifetime. [4] [7] They occur most frequently between the ages of 16 and 35 years. [7] Recurrences are common. [7]

  7. List of antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_antibiotics

    They are competitive inhibitors of the enzyme dihydropteroate synthetase, DHPS. DHPS catalyses the conversion of PABA ( para -aminobenzoate ) to dihydropteroate , a key step in folate synthesis. Folate is necessary for the cell to synthesize nucleic acids (nucleic acids are essential building blocks of DNA and RNA ), and in its absence cells ...

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  9. Assessment of kidney function - Wikipedia

    en.wikipedia.org/wiki/Assessment_of_kidney_function

    One of the measures of kidney function is the glomerular filtration rate (GFR). Other tests that can assess the function of the kidneys include assessment of electrolyte levels such as potassium and phosphate, assessment of acid-base status by the measurement of bicarbonate levels from a vein, and assessment of the full blood count for anaemia.