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Aniracetam (brand names Draganon, Sarpul, Ampamet, Memodrin, Referan), also known as N-anisoyl-2-pyrrolidinone, is a racetam which is sold in Europe as a prescription drug. It is not approved by the Food and Drug Administration for use in the United States as a prescription medication or dietary supplement .
Like some ampakines, some racetams, such as piracetam and aniracetam, are positive allosteric modulators of the AMPA receptor. [7] Racetams are understood to work by allosterically modulating glutamate receptors, specifically AMPA receptors, leading to Ca 2+ influx that is excitatory. [8]
Oxiracetam is well absorbed from the gastrointestinal tract with a bioavailability of 56-82%. [6] Peak serum levels are reached within one to three hours after a single 800 mg or 2000 mg oral dose, with the maximal serum concentration reaching between 19 and 31 μg/ml at these doses.
The racetams have poorly understood mechanisms, although piracetam and aniracetam are known to act as positive allosteric modulators of AMPA receptors and appear to modulate cholinergic systems. [27] Similar compounds, such as noopept and aloracetam , do not meet the chemical definition for being a racetam, though they are considered "racetam ...
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The racetams have poorly understood mechanisms, although piracetam and aniracetam are known to act as positive allosteric modulators of AMPA receptors and appear to modulate cholinergic systems. [33] Similar compounds, such as noopept and aloracetam , do not meet the chemical definition for being a racetam, though they are considered "racetam ...
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