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In population genetics, F-statistics (also known as fixation indices) describe the statistically expected level of heterozygosity in a population; more specifically the expected degree of (usually) a reduction in heterozygosity when compared to Hardy–Weinberg expectation.
Hardy's paper was focused on debunking the view that a dominant allele would automatically tend to increase in frequency (a view possibly based on a misinterpreted question at a lecture [1]). Today, tests for Hardy–Weinberg genotype frequencies are used primarily to test for population stratification and other forms of non-random mating.
Allele frequency, or gene frequency, is the relative frequency of an allele (variant of a gene) at a particular locus in a population, expressed as a fraction or percentage. [1] Specifically, it is the fraction of all chromosomes in the population that carry that allele over the total population or sample size.
Stokes' law is important for understanding the swimming of microorganisms and sperm; also, the sedimentation of small particles and organisms in water, under the force of gravity. [ 5 ] In air, the same theory can be used to explain why small water droplets (or ice crystals) can remain suspended in air (as clouds) until they grow to a critical ...
In the process of substitution, a previously non-existent allele arises by mutation and undergoes fixation by spreading through the population by random genetic drift or positive selection. Once the frequency of the allele is at 100%, i.e. being the only gene variant present in any member, it is said to be "fixed" in the population. [1]
Selection coefficient, usually denoted by the letter s, is a measure used in population genetics to quantify the relative fitness of a genotype compared to other genotypes. . Selection coefficients are central to the quantitative description of evolution, since fitness differences determine the change in genotype frequencies attributable to selecti
Genetic equilibrium is the condition of an allele or genotype in a gene pool (such as a population) where the frequency does not change from generation to generation. [1] Genetic equilibrium describes a theoretical state that is the basis for determining whether and in what ways populations may deviate from it.
The quantity pq is maximized when there is an equal frequency of each gene, when =. In the GSM, the rate of change Δ Q {\displaystyle \Delta Q} is proportional to the genetic variation. The mean population fitness W ¯ {\displaystyle {\overline {W}}} is a measure of the overall fitness of the population.