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Transcription factor II H (TF II H) is an important protein complex, having roles in transcription of various protein-coding genes and DNA nucleotide excision repair (NER) pathways. TF II H first came to light in 1989 when general transcription factor-δ or basic transcription factor 2 was characterized as an indispensable transcription factor ...
229906 Ensembl ENSG00000137947 ENSMUSG00000028271 UniProt Q00403 P62915 RefSeq (mRNA) NM_001514 NM_145546 RefSeq (protein) NP_001505 NP_663521 Location (UCSC) Chr 1: 88.85 – 88.89 Mb Chr 3: 142.47 – 142.49 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transcription factor II B (TFIIB) is a general transcription factor that is involved in the formation of the RNA polymerase II ...
Transcription factor TF II A is a nuclear protein involved in the RNA polymerase II-dependent transcription of DNA. [1] TF II A is one of several general (basal) transcription factors that are required for all transcription events that use RNA polymerase II. Other GTFs include TF II D, a complex composed of the TATA binding protein TBP and TBP ...
The minimal PIC includes RNA polymerase II and six general transcription factors: TF II A, TF II B, TF II D, TF II E, TF II F, and TF II H. Additional regulatory complexes (such as the mediator coactivator [ 5 ] and chromatin remodeling complexes) may also be components of the PIC.
Transcription factor glossary; ... a transcription factor (TF) ... II.B.3.b Latent cytoplasmic factors – residing in the cytoplasm when inactive. Structurally and ...
Transcription factor II D (TF II D) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. RNA polymerase II holoenzyme is a form of eukaryotic RNA polymerase II that is recruited to the promoters of protein-coding genes in living cells.
Transcription factor II E (TF II E) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. [1] It is a tetramer of two alpha and two beta chains and interacts with TAF6/TAFII80, ATF7IP, and varicella-zoster virus IE63 protein.
TF II F is encoded by the GTF2F1, GTF2F2, and GTF2F2L genes. [4] [5] [6] TF II F binds to RNA polymerase II when the enzyme is already unbound to any other transcription factor, thus preventing it from contacting DNA outside the promoter. Furthermore, TF II F stabilizes the RNA polymerase II while it's contacting TBP and TF II B.