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  2. General transcription factor - Wikipedia

    en.wikipedia.org/wiki/General_transcription_factor

    A transcription factor is a protein that binds to specific DNA sequences (enhancer or promoter), either alone or with other proteins in a complex, to control the rate of transcription of genetic information from DNA to messenger RNA by promoting (serving as an activator) or blocking (serving as a repressor) the recruitment of RNA polymerase.

  3. Transcription factor - Wikipedia

    en.wikipedia.org/wiki/Transcription_factor

    The protein version of the transcription factor is detectable by using specific antibodies. The sample is detected on a western blot. By using electrophoretic mobility shift assay (EMSA), [88] the activation profile of transcription factors can be detected.

  4. TBP-associated factor - Wikipedia

    en.wikipedia.org/wiki/TBP-associated_factor

    It is a part of the transcription initiation factor TFIID multimeric protein complex. It also makes up many other factors, including SL1. They mediate the formation of the transcription preinitiation complex, a step preceding transcription of DNA to RNA by RNA polymerase II. TAFs have a signature N-terminal histone-like fold domain (HFD). [1]

  5. Transcription factor II A - Wikipedia

    en.wikipedia.org/wiki/Transcription_Factor_II_A

    Transcription factor TF II A is a nuclear protein involved in the RNA polymerase II-dependent transcription of DNA. [1] TF II A is one of several general (basal) transcription factors ( GTFs ) that are required for all transcription events that use RNA polymerase II.

  6. TEAD1 - Wikipedia

    en.wikipedia.org/wiki/TEAD1

    Download as PDF; Printable version; In other projects ... and transcription factor 13 ... the increase of TEAD expression can be detected in basal-like breast cancers ...

  7. TAF1 - Wikipedia

    en.wikipedia.org/wiki/TAF1

    Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.

  8. TAF12 - Wikipedia

    en.wikipedia.org/wiki/TAF12

    66464 Ensembl ENSG00000120656 ENSMUSG00000028899 UniProt Q16514 Q8VE65 RefSeq (mRNA) NM_001135218 NM_005644 NM_025579 RefSeq (protein) NP_001128690 NP_005635 NP_079855 Location (UCSC) Chr 1: 28.59 – 28.65 Mb Chr 4: 132 – 132.02 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transcription initiation factor TFIID subunit 12 is a protein that in humans is encoded by the TAF12 gene ...

  9. TAF6 - Wikipedia

    en.wikipedia.org/wiki/TAF6

    TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation.