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Remarkably Bright Creatures is a novel by American author Shelby Van Pelt. It was published in May 2022 by Ecco Press. It has been on the New York Times hardcover fiction best-seller list multiple times. [1] It was awarded the 2023 McLaughlin-Esstman-Stearns First Novel Prize by the Writer's Center. [2]
Author Shelby Van Pelt talks about her octopus narrator, character and inspiration before the finale event for 14th Read Together Palm Beach County.
With multiple sclerosis, inflammation settles in the central nervous system after immune cells attack the coating on nerves; lupus can cause inflammation in the heart, brain, kidney, and other organs.
Inflammation is a generic response, and therefore is considered a mechanism of innate immunity, whereas adaptive immunity is specific to each pathogen. [2] Inflammation is a protective response involving immune cells, blood vessels, and molecular mediators. The function of inflammation is to eliminate the initial cause of cell injury, clear out ...
Chronic systemic inflammation is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system.It can contribute to the development or progression of certain conditions such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease, autoimmune and neurodegenerative ...
Tumor necrosis factor (TNF), formerly known as TNF-α, is a chemical messenger produced by the immune system that induces inflammation. [5] TNF is produced primarily by activated macrophages, and induces inflammation by binding to its receptors on other cells. [6]
Neuroinflammation is widely regarded as chronic, as opposed to acute, inflammation of the central nervous system. [5] Acute inflammation usually follows injury to the central nervous system immediately, and is characterized by inflammatory molecules, endothelial cell activation, platelet deposition, and tissue edema. [6]
While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. [1] The underlying mechanism involves the body's immune system attacking the joints. [1] This results in inflammation and thickening of the joint capsule. [1] It also affects the underlying bone and cartilage. [1]