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Drosophila melanogaster has two Cdc25s, known as string and twine, which control mitosis [8] and meiosis, [9] respectively. Most other model organisms examined have three Cdc25s, designated Cdc25A, Cdc25B, and Cdc25C. An exception is the nematode Caenorhabditis elegans, which has four distinct Cdc25 genes (Cdc-25.1 to Cdc-25.4). [10]
Polycomb-group proteins are well known for silencing Hox genes through modulation of chromatin structure during embryonic development in fruit flies (Drosophila melanogaster). They derive their name from the fact that the first sign of a decrease in PcG function is often a homeotic transformation of posterior legs towards anterior legs, which ...
Drosophila melanogaster is a species of fly (an insect of the order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly , or less commonly the " vinegar fly", " pomace fly", [ a ] [ 5 ] or " banana fly". [ 6 ]
The Drosophila Interactions Database (DroID) is an online database of Drosophila gene and protein interactions. [1] It was developed by Russell L. Finley's laboratory at Wayne State University School of Medicine in 2008 and has been funded by the National Human Genome Research Institute, National Institutes of Health's National Center for Research Resources, Michigan Proteome Consortium, and ...
Drosophila is a genus of flies of the family Drosophilidae. It comprises over 1600 described species, [ 1 ] [ 2 ] but is estimated to have several thousands. [ 3 ] Alfred Sturtevant divided Drosophila into a number of subgenera , including Drosophila , Sophophora , and Dorsilopha .
Flightless fruit flies (Order Diptera) encompass a variety of different species of fly, such as Drosophila melanogaster, Bactrocera cucurbitae, Bactrocera dorsalis, and Drosophila hydei, with genetic mutations that cause them to be flightless. [1]
The role of Suppressor of Fused (SUFU) has been enhanced in vertebrates compared to Drosophila where its role is relatively minor. Costal-2 is particularly important in Drosophila. The protein kinase Fused is a regulator of SUFU in Drosophila, but may not play a role in the Hh pathway of vertebrates. [71]
In this experiment, researchers screened for different mutations in D. melanogaster embryos that affected the neural development of axons in the central nervous system. They found that the mutations in commissureless genes ( Slit genes) lead to the growth cones that typically cross the midline remaining on their own side.