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Section of bone marrow core biopsy as seen under the microscope (stained with H&E). The preferred sites for the procedure. Bone marrow samples can be obtained by aspiration and trephine biopsy. Sometimes, a bone marrow examination will include both an aspirate and a biopsy.
Bone marrow examination is the pathologic analysis of samples of bone marrow obtained via biopsy and bone marrow aspiration. Bone marrow examination is used in the diagnosis of a number of conditions, including leukemia, multiple myeloma, anemia, and pancytopenia. The bone marrow produces the cellular elements of the blood, including platelets ...
[6] [7] Perls's procedure may be used to identify excess iron deposits such as hemosiderin deposits (hemosiderosis) and in conditions such as hereditary hemochromatosis. [8] Perls Prussian blue is commonly used on bone marrow aspirates to indicate levels of iron storage [4] and may provide reliable evidence of iron deficiency. [7]
Bone: A bone biopsy is a procedure in which bone samples are removed to find out if cancer or infection or other abnormal cells are present. A bone biopsy involves the outer layers of bone, unlike a bone marrow biopsy, which involves the innermost part of the bone. Bone biopsy should as rule be done after all necessary imagings performed.
The Jamshidi needle is a trephine needle for performing bone marrow biopsy, whereby a cylindrical sample of tissue, a core biopsy specimen, is obtained. It is a cylindrical needle with a tapered cutting tip. [1] The tapered end reduces the potential of crush artifact. [2] It is the most commonly used needle for performing bone marrow biopsies. [3]
In cases of a sickle cell bone marrow transplant, the best results come from a sibling. A sibling HLA match gives the procedure a 95% success rate, as opposed to a rate of around 78% with an ...
Romanowsky-type stains are widely used in the examination of blood, in the form of blood films, and in the microscopic examination of bone marrow biopsies and aspirate smears. [1] [23] Examination of both blood and bone marrow can be of importance in the diagnosis of a variety of blood diseases.
Wright's stain is a hematologic stain that facilitates the differentiation of blood cell types. It is classically a mixture of eosin (red) and methylene blue dyes. It is used primarily to stain peripheral blood smears, urine samples, and bone marrow aspirates, which are examined under a light microscope.
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