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Prednisolone has a relatively short half-life, ranging 2–4 hours. It also has a large therapeutic window, considering the dosage required to produce a therapeutic effect is a few times higher than what the body naturally produces. [14] Prednisolone is 70–90% plasma protein bound, it binds to proteins such as albumin. [14]
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An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
Prednisolone: 4 0.8 16–36 Methylprednisolone: 5–7.5 0.5 18–40 Dexamethasone: 25–80 0 36–54 Betamethasone: 25–30 0 36–54 Triamcinolone: 5 0 12–36 Deflazacort: 6.5 – 1.3 Fludrocortisone acetate: 15 200 24 Deoxycorticosterone acetate: 0 20 – Aldosterone: 0.3 200–1000 – Beclometasone
Symptoms of overdose may include altered mental status with psychosis, burning or itching skin, seizures, deafness, depression, dry skin, heart rhythm disturbances, hypertension, increase appetite, increased infection risk, muscle weakness, nausea and vomiting, nervousness, sleepiness, stopping of menstrual cycle, swelling in lower legs, weak bones, weakness, and worsening of health conditions.
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A compressor map is a chart which shows the performance of a turbomachinery compressor. This type of compressor is used in gas turbine engines, for supercharging reciprocating engines and for industrial processes, where it is known as a dynamic compressor. A map is created from compressor rig test results or predicted by a special computer program.
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