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In females, the paramesonephric ducts give rise to the uterine tubes, uterus, and upper portion of the vagina, while the mesonephric ducts degenerate due to the absence of male androgens. In contrast, the paramesonephric ducts begin to proliferate and differentiate in a cranial-caudal progression to form the aforementioned structures.
In the female, the paramesonephric ducts persist and undergo further development. The portions which lie in the genital cord [citation needed] fuse to form the uterus and vagina. This fusion of the paramesonephric ducts begins in the third month, and the septum formed by their fused medial walls disappears from below upward.
The ducts pass backward lateral to the Wolffian ducts, but toward the posterior end of the embryo they cross to the medial side of these ducts, and thus come to lie side by side between and behind the latter—the four ducts forming what is termed the common genital cord, to distinguish it from the genital cords of the germinal epithelium seen ...
It is located in the developing fetus between the orifices of the mesonephric ducts on the urogenital sinus. [1] The uterovaginal primoridium, which is a fusion of the caudal ends of paramesonephric ducts, contacts the dorsal wall of the urogenital sinus and, induces the formation of the sinus tubercle. This occurs in both sexes:
m, m. Right and left Müllerian ducts uniting together and running with the Wolffian ducts in gc, the genital cord: m. Müllerian duct, the upper part of which remains as the hydatid of Morgagni; the lower part, represented by a dotted line descending to the prostatic utricle, constitutes the occasionally existing cornu and tube of the uterus ...
Four types of uterine malformations. The uterus is formed during embryogenesis by the fusion of the two paramesonephric ducts (also called Müllerian ducts). This process usually fuses the two Müllerian ducts into a single uterine body but fails to take place in these affected women who maintain their double Müllerian systems.
The Müllerian ducts are also referred to as paramesonephric ducts, referring to ducts next to (para) the mesonephric (Wolffian) duct during foetal development. Paramesonephric ducts are paired ducts derived from the embryo, and for females develop into the uterus , uterine tubes , cervix and upper two-thirds of the vagina. [ 6 ]
As development proceeds, the intermediate mesoderm differentiates sequentially along the anterior-posterior axis into three successive stages of the early mammalian and avian urogenital system, named pronephros, mesonephros and metanephros respectively (anamniote embryos form only a pronephros and mesonephros). [2]