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Similar to other local anesthetics, benzonatate is a potent voltage-gated sodium channel blocker. [22] After absorption and circulation to the respiratory tract, benzonatate acts as a local anesthetic , decreasing the sensitivity of vagal afferent fibers and stretch receptors in the bronchi , alveoli , and pleura in the lower airway and lung .
Sodium benzoate also known as benzoate of soda is the sodium salt of benzoic acid, widely used as a food preservative (with an E number of E211) and a pickling agent. It appears as a white crystalline chemical with the formula C 6 H 5 COONa.
The following is a list of chemicals published as a requirement of Safe Drinking Water and Toxic Enforcement Act of 1986, commonly known as California Proposition 65, that are "known to the state to cause cancer or reproductive toxicity" as of January 3, 2020. [1]
Denatonium, usually available as denatonium benzoate (under trade names such as Denatrol, BITTERANT-b, BITTER+PLUS, Bitrex, Bitrix, and Aversion) and as denatonium saccharinate (BITTERANT-s), is the most bitter chemical compound known, with bitterness thresholds of 0.05 ppm for the benzoate and 0.01 ppm for the saccharinate. [1]
Diethylamino hydroxybenzoyl hexyl benzoate is an organic compound used in sunscreens to absorb UVA radiation. It is marketed as Parsol DHHB by DSM and as Uvinul A Plus by BASF. DHHB has an absorption maximum of 354 nm. [1] [2] DHHB has excellent photostability and compatibility with other UV absorbers and other cosmetic ingredients. [3]
Signs and symptoms of pregnancy are common, benign conditions that result from the changes to the body that occur during pregnancy. Signs and symptoms of pregnancy typically change as pregnancy progresses, although several symptoms may be present throughout. Depending on severity, common symptoms in pregnancy can develop into complications. [1]
Sodium phenylacetate/sodium benzoate, sold under the brand name Ammonul among others, is a fixed-dose combination medication used to treat high blood ammonia. [1] It is a combination of sodium phenylacetate and sodium benzoate .
Contraindicated in pregnancy: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.