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  2. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    However, in clinical trials, high blood pressure was reported in just one percent of patients taking 2.5-milligram tadalafil and three percent of patients taking the 5-milligram dose.

  3. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    Tadalafil is a widely used medication, mostly prescribed to treat ED and sometimes to treat the symptoms of benign prostatic hyperplasia (BPH) as well as pulmonary arterial hypertension (under the ...

  4. Tadalafil - Wikipedia

    en.wikipedia.org/wiki/Tadalafil

    Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. [5] [6] [8] It is taken by mouth. [8] Onset is typically within half an hour and the duration is up to 36 hours. [8]

  5. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    These ED drugs belong to a class of medications called PDE5 inhibitors, short for phosphodiesterase type 5 inhibitors. They suppress PDE5 (an enzyme in the smooth muscle cells of your blood ...

  6. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    PDE5 inhibitors are contraindicated within 24 hours (or 48 hours with tadalafil) of taking alpha-blockers, soluble guanylate cyclase stimulators, or nitrate medications such as isosorbide mononitrate or isosorbide dinitrate. [1] Concurrent use of these medications can lead to life-threatening low blood pressure. [5]

  7. Macitentan/tadalafil - Wikipedia

    en.wikipedia.org/wiki/Macitentan/tadalafil

    Macitentan/tadalafil, sold under the brand name Opsynvi, is a fixed dose combination medication used for the treatment of pulmonary arterial hypertension. [3] It contains macitentan, an endothelin receptor antagonist (ERA); and tadalafil, a phosphodiesterase 5 (PDE5) inhibitor.

  8. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

    www.aol.com/4-common-ed-pills-weighing-141800609...

    Tadalafil has a half-life of 17.5 hours — it remains active in your body for far longer than other ED medications. A single dose of tadalafil ... medications used to treat high blood pressure ...

  9. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    Chlorthalidone is the thiazide drug that is most strongly supported by the evidence as providing a mortality benefit; in the ALLHAT study, a chlorthalidone dose of 12.5 mg was used, with titration up to 25 mg for those subjects who did not achieve blood pressure control at 12.5 mg. Chlorthalidone has repeatedly been found to have a stronger ...