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  2. Spinocerebellar ataxia type 1 - Wikipedia

    en.wikipedia.org/wiki/Spinocerebellar_ataxia_type_1

    SCA1 positive mice haplodeficient in 14-3-3ε +/-were shown not to exhibit cerebellar degeneration but still exhibited lethal bulbar degeneration, suggesting that cerebellar atrophy may be related to increased stability of the expanded ataxin 1 protein and that there may be different pathogenic mechanisms for different regions of the brain. [26]

  3. Spinocerebellar ataxia - Wikipedia

    en.wikipedia.org/wiki/Spinocerebellar_ataxia

    Spinocerebellar ataxia (SCA) is a progressive, degenerative, [1] genetic disease with multiple types, each of which could be considered a neurological condition in its own right. An estimated 150,000 people in the United States have a diagnosis of spinocerebellar ataxia at any given time. SCA is hereditary, progressive, degenerative, and often ...

  4. Management of scoliosis - Wikipedia

    en.wikipedia.org/wiki/Management_of_scoliosis

    Implants that aim to delay spinal fusion and to allow more spinal growth in young children is the gold standard for surgical treatment of early onset scoliosis. Surgery without fusion can be divided into three principles: distraction of the entire spine, compression of the short segment of spine, and guided-growth techniques.

  5. Degenerative disc disease - Wikipedia

    en.wikipedia.org/wiki/Degenerative_disc_disease

    Degenerative disc disease (DDD) is a medical condition typically brought on by the aging process in which there are anatomic changes and possibly a loss of function of one or more intervertebral discs of the spine. [1] DDD can take place with or without symptoms, but is typically identified once symptoms arise.

  6. Friedreich's ataxia - Wikipedia

    en.wikipedia.org/wiki/Friedreich's_ataxia

    Friedreich's ataxia (FRDA) is a rare, inherited, autosomal recessive neurodegenerative disorder that primarily affects the nervous system, causing progressive damage to the spinal cord, peripheral nerves, and cerebellum, leading to impaired muscle coordination . The condition typically manifests in childhood or adolescence, with initial ...

  7. Spinal disease - Wikipedia

    en.wikipedia.org/wiki/Spinal_disease

    There are many recognized spinal diseases, some more common than others. Spinal disease also includes cervical spine diseases, which are diseases in the vertebrae of the neck. A lot of flexibility exists within the cervical spine and because of that, it is common for an individual to damage that area, especially over a long period of time.

  8. Subacute combined degeneration of spinal cord - Wikipedia

    en.wikipedia.org/wiki/Subacute_combined...

    Subacute combined degeneration of spinal cord, also known as myelosis funiculus, or funicular myelosis, [1] also Lichtheim's disease, [2] [3] and Putnam-Dana syndrome, [4] refers to degeneration of the posterior and lateral columns of the spinal cord as a result of vitamin B 12 deficiency (most common).

  9. Cervical spondylotic myelopathy - Wikipedia

    en.wikipedia.org/wiki/Cervical_spondylotic...

    Cervical Spondylotic Myelopathy (CSM) is a disorder characterised by the age-related deterioration of the cervical spinal cord. [1] Referred to be a range of different but related terms, a global consensus process selected Degenerative Cervical Myelopathy as the new overarching disease term. [2]

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