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  2. Antisynthetase syndrome - Wikipedia

    en.wikipedia.org/wiki/Antisynthetase_syndrome

    Those with anti-Jo1 antibodies had less remission of myositis and more relapses than those with anti-PL-12 and anti-PL-7 antibodies. [64] Anti-Jo-1 and anti-Ro52 antibodies co-occurring were linked to an increased risk of neoplasm, a symptomatic severe variant of interstitial lung disease, myositis, and arthritis exacerbation. [20]

  3. Myocarditis-myositis-myasthenia gravis overlap syndrome

    en.wikipedia.org/wiki/Myocarditis-Myositis...

    Myocarditis-myositis-myasthenia gravis overlap syndrome (IM3OS) is a rare immune-related adverse event primarily associated with the use of immune checkpoint inhibitors (ICIs). These ICIs, which have been incorporated into the treatment of various malignancies , function by activating the immune system to detect and attack cancer cells .

  4. Mixed connective tissue disease - Wikipedia

    en.wikipedia.org/wiki/Mixed_connective_tissue...

    Two investigations have provided evidence that anti-RNP antibodies have a role in the development of MCTD by linking antibody emergence to clinical illness. [ 63 ] [ 64 ] Beyond antibody formation, B cells can serve in a variety of other important immunological pathways, including as antigen presentation, pathogenic cytokine secretion, and ...

  5. Statin-associated autoimmune myopathy - Wikipedia

    en.wikipedia.org/wiki/Statin-associated...

    These antibodies are known to also occur in people who do not take statin medications. [3] Conversely, these antibodies are absent in people who take statin medications but do not have myopathy. Thus, the presence of anti-HMG CoA reductase antibodies in someone who uses a statin and has myopathy strongly supports the diagnosis. [ 3 ]

  6. Polymyositis - Wikipedia

    en.wikipedia.org/wiki/Polymyositis

    Polymyositis and the associated inflammatory myopathies have an associated increased risk of cancer. [3] The features they found associated with an increased risk of cancer were older age, age greater than 45, male sex, difficulty swallowing, death of skin cells, cutaneous vasculitis, rapid onset of myositis (<4 weeks), elevated creatine kinase, higher erythrocyte sedimentation rate and higher ...

  7. Scleromyositis - Wikipedia

    en.wikipedia.org/wiki/Scleromyositis

    Scleromyositis, is an autoimmune disease (a disease in which the immune system attacks the body). People with scleromyositis have symptoms of both systemic scleroderma and either polymyositis or dermatomyositis, and is therefore considered an overlap syndrome.

  8. Benign acute childhood myositis - Wikipedia

    en.wikipedia.org/.../Benign_acute_childhood_myositis

    in 1957 Lundberg reported on a group of patients with a condition he named myalgia cruris epidemica, [7] seemingly the first description of BACM. Other terms later used include influenza-associated myositis, viral myositis, acute myositis [2] Middleton and colleagues reported on BACM as severe myositis after influenza in 1970. [8]

  9. Dermatomyositis - Wikipedia

    en.wikipedia.org/wiki/Dermatomyositis

    Eighty percent of adults [5] and sixty percent of children with juvenile dermatomyositis have a myositis-specific antibody (MSA). [6] Although no cure for the condition is known, treatments generally improve symptoms. [1] Treatments may include medication, physical therapy, exercise, heat therapy, orthotics, assistive devices, and rest. [1]