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Lithium Lithium is the "classic" mood stabilizer, the first to be approved by the US FDA, and still popular in treatment. Therapeutic drug monitoring is required to ensure lithium levels remain in the therapeutic range: 0.6 to 0.8 or 0.8–1.2 mEq/L (or millimolar).
A number of anti-convulsant drugs are used as mood stabilizers, and the suspected mechanism is related to the theory that mania can "kindle" further mania, similar to the kindling model of seizures. [2] Valproic acid, or valproate, was one of the first anti-convulsants tested for use in bipolar disorder.
Anticonvulsants are also increasingly being used in the treatment of bipolar disorder [2] [3] and borderline personality disorder, [4] since many seem to act as mood stabilizers, and for the treatment of neuropathic pain. [5] Anticonvulsants suppress the excessive rapid firing of neurons during seizures. [6]
Bipolar disorder is a long-term mood disorder characterized by major fluctuations in mood — both high and low — that can impact daily functioning and behavior. Bipolar Disorder: 4 Types & What ...
The study found a link between prescription folic acid — which is inexpensive and widely available — and a 44% lower rate of suicide attempts.
The mechanism of action of mood stabilizers is not well understood. Common non-antipsychotic mood stabilizers include: Lithium (Lithobid, Eskalith), the oldest mood stabilizer; Anticonvulsants Carbamazepine (Tegretol) and the related compound oxcarbazepine (Trileptal) Valproic acid, and salts (Depakene, Depakote) Lamotrigine (Lamictal)
Lithium and the anticonvulsants carbamazepine, lamotrigine, and valproic acid are classed as mood stabilizers due to their effect on the mood states in bipolar disorder. [120] Lithium has the best overall evidence and is considered an effective treatment for acute manic episodes, preventing relapses, and bipolar depression.
This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress.. The list is ordered alphabetically according to the condition or conditions, then by the generic name of each medication.
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