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  2. DNA mismatch repair - Wikipedia

    en.wikipedia.org/wiki/DNA_mismatch_repair

    Mismatch repair is a highly conserved process from prokaryotes to eukaryotes.The first evidence for mismatch repair was obtained from S. pneumoniae (the hexA and hexB genes).

  3. Assay - Wikipedia

    en.wikipedia.org/wiki/Assay

    An assay (analysis) is never an isolated process, as it must be accompanied with pre- and post-analytic procedures. Both the communication order (the request to perform an assay plus related information) and the handling of the specimen itself (the collecting, documenting, transporting, and processing done before beginning the assay) are pre-analytic steps.

  4. Blood compatibility testing - Wikipedia

    en.wikipedia.org/wiki/Blood_compatibility_testing

    Blood compatibility testing is routinely performed before a blood transfusion.The full compatibility testing process involves ABO and RhD (Rh factor) typing; screening for antibodies against other blood group systems; and crossmatching, which involves testing the recipient's blood plasma against the donor's red blood cells as a final check for incompatibility.

  5. Nick (DNA) - Wikipedia

    en.wikipedia.org/wiki/Nick_(DNA)

    In a lab setting, this can be used to introduce fluorescent or other tagged nucleotides by purposefully inducing site-specific, single-stranded nicks in DNA in vitro and then adding the nicked DNA to an environment rich in DNA polymerase and tagged nucleotide. The DNA polymerase then replaces the DNA nucleotides with the tagged ones, starting ...

  6. Biosafety - Wikipedia

    en.wikipedia.org/wiki/Biosafety

    Secondly, the laboratory supervisor, who reports to the laboratory director, is responsible for organizing regular training sessions on laboratory safety. [9] The third point, the personnel must be informed about any special hazards and be required to review the safety or operations manual and adhere to established practices and procedures. The ...

  7. Biosafety level - Wikipedia

    en.wikipedia.org/wiki/Biosafety_level

    A laboratory-specific biosafety manual must be drafted which details how the laboratory will operate in compliance with all safety requirements. [ 21 ] All laboratory personnel are provided medical surveillance and offered relevant immunizations (where available) to reduce the risk of an accidental or unnoticed infection.

  8. Cross-matching - Wikipedia

    en.wikipedia.org/wiki/Cross-matching

    Cross-matching or crossmatching is a test performed before a blood transfusion as part of blood compatibility testing. Normally, this involves adding the recipient's blood plasma to a sample of the donor's red blood cells. If the blood is incompatible, the antibodies in the recipient's plasma will bind to antigens on the donor red blood cells.

  9. Evolutionary mismatch - Wikipedia

    en.wikipedia.org/wiki/Evolutionary_mismatch

    Evolutionary mismatch (also "mismatch theory" or "evolutionary trap") is the evolutionary biology concept that a previously advantageous trait may become maladaptive due to change in the environment, especially when change is rapid. It is said this can take place in humans as well as other animals.

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